Fig. 12. Schematic representation of LINC complex and SUN-KASH proteins that span the nuclear envelope. LINC complexes facilitate transferring the external mechanical cues to the nucleus. The components of LINC complexes are connected to INM and ONM through their SUN domains and KASH domains. These domains as part of the LINC complex molecular chain connecting the cytoskeleton with the nucleoskeleton (Reprinted with permission, Elsevier, for citation see [109]).